How long after taking ibuprofen can i take alka-seltzer

How many Alka-Seltzer Plus Cold can I take? The general recommendation is to not take more than 8 Alka-Seltzer Plus Cold pills in a 24-hour period. Do not use more than directed. Taking more than recommended can result in unwanted side effects such as nausea, vomiting, diarrhea, headache and stomach pain.

How long after taking ibuprofen can i take alka-seltzer. Taking aspirin during this time may cause bleeding problems. For diabetic patients taking aspirin- or sodium salicylate-containing medicine: False urine sugar test results may occur: If you take 8 or more 325-mg doses of aspirin every day for several days in a row. If you take 8 or more 325-mg or 4 or more 500-mg doses of sodium salicylate.

One ingredient in this product is acetaminophen.Taking too much acetaminophen may cause serious (possibly fatal) liver disease.Adults should not take more than 4000 milligrams (4 grams) of ...

Applies to: Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while …Tums are considered safe for pregnancy but Alka Seltzer should be avoided if it is a formulation that contains aspirin. Natural ways to address heartburn during pregnancy include eating several hours before bed, avoiding certain foods, having smaller meals and eating more slowly. Yogurt, ginger and water can help reduce heartburn in pregnant …We would like to show you a description here but the site won’t allow us.This includes aspirin, ibuprofen (Advil®), naproxen sodium (Aleve®), Alka-Seltzer®, acetaminophen (Tylenol®), Excedrin® and certain antibiotics and medications for fungal infections, anxiety ...ALKA-SELTZER- anhydrous citric acid, ... take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcoholic drinks every day while using this product; take more or for a longer time than directed; Do not use if you are allergic to aspirin or any other pain reliever/fever reducerAdditionally, some types of Alka-Seltzer contain aspirin, so if the one you are taking does, then it is best to avoid taking ibuprofen at all. How long after taking Alka-Seltzer Can I take Tylenol? It is generally recommended to wait at least 2-3 hours before taking Tylenol after consuming Alka-Seltzer.How long do i have to wait to take xanax (alprazolam) after taking alka seltzer? A doctor has provided 1 answer. Dr. Alan Ali answered. Specializes in Psychiatry. Xanax (alprazolam): As prescribed, but usually at least half hour after alka seltzer.

Answer. It is safe to combine DayQuil and ibuprofen. There is no known drug interaction between them. It is important to note that there are several 'DayQuil' products available on the market, including: While all these products contain slightly different ingredients, they are all safe to take with ibuprofen.Xanax (alprazolam): As prescribed, but usually at least half hour after alka seltzer. ... and breasfeed as long as you wait 4 hours.Taking it for 1.5 months. Should I ...Sulindac: learn about side effects, dosage, special precautions, and more on MedlinePlus People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) su...Avoid taking aspirin or aspirin-containing medications for one week following gastric sleeve surgery. These can include: Bayer Aspirin; Alka-Seltzer; Excedrin; Ecotrin; Avoiding these medications prevents any tissue irritation within the gastrointestinal tract. Avoid non-steroidal anti-inflammatory drugs (NSAIDs) for one month after surgerytake a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcoholic drinks every day while using this product take more or for a longer time than directedCommon side effects of Alka-Seltzer Plus Day and Night Cold and Flu may include: drowsiness; constipation, diarrhea, upset stomach, vomiting; or. feeling restless or excited. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Additionally, some types of Alka-Seltzer contain aspirin, so if the one you are taking does, then it is best to avoid taking ibuprofen at all. How long after taking Alka-Seltzer Can I take Tylenol? It is generally recommended to wait at least 2-3 hours before taking Tylenol after consuming Alka-Seltzer.Can i take alka seltzer plus night time and m367 (acetaminophen and hydrocodone 325 mg / 10 mg) together? 2 doctors weighed in across 2 answers. can i take alma seltzer with gabapentin and naproxen?: Several problems: with …Uses. This product is used to relieve symptoms of extra gas such as belching, bloating, and feelings of pressure/discomfort in the stomach /gut. Simethicone helps break up gas bubbles in the gut ... Applies to: Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines.

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Nov 6, 2023 · Dizziness. Feeling nervous and excitable. Not able to sleep. Feeling sleepy. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional. conditions, or Parkinson's disease), or for 2 weeks after stopping. the MAOI drug. If you do not know if your prescription drug. contains an MAOI, ask a doctor or pharmacist before taking this. product.Dec 30, 2020 · Mild stomach pain, nausea, heartburn. Feeling restless, jittery, or irritated. Mild stomach pain, nausea, or heartburn. Slight ringing in your ears. Trouble sleeping. Learn about Alka-Seltzer: What it is used for, how to take Alka-Seltzer, serious side effects, food and drug interactions, forms, doses, safe storage, and FAQs. Answer. It is safe to combine DayQuil and ibuprofen. There is no known drug interaction between them. It is important to note that there are several 'DayQuil' products available on the market, including: While all these products contain slightly different ingredients, they are all safe to take with ibuprofen.If you must use both medications, take the ibuprofen at least 8 hours before or 30 minutes after you take the aspirin and caffeine (non-enteric coated form).Specializes in Pediatrics. Ask own doctor: Tylenol has acetaminophen. Alka Seltzer Plus Cold has aspirin along with other ingredients. If taken together, they shouldn't cause an overdosing problem (because they don't have the same ingredients). However, if both are taken, a person would be doubling up on anti-inflammatory anti-pyretic pain ...

Alka-Seltzer Plus Night-Time Cold & Flu. Generic name: acetaminophen, dextromethorphan, doxylamine, and phenylephrine [ ah-EET-a-MIN-oh-fen, DEX-troe-me-THOR-fan, dox-IL-a-meen, and-FEN-il-EFF-rin ] Brand names: Alka-Seltzer Plus Cold And Flu Day Night Maximum Strength, Alka-Seltzer Plus Day and Night Cold and Flu, Alka …Alka- Seltzer ®. Anhydrous citric acid / Antacid Aspirin ( NSAID) / Analgesic Sodium bicarbonate / Antacid. Fast Relief of: Heartburn Upset Stomach Acid Indigestion with Headache Body Aches. ORIGINAL. 24 EFFERVESCENT TABLETS. ALKA-SELTZER ORIGINAL anhydrous citric acid, aspirin, and sodium bicarbonate tablet, effervescent. Product Information.If you will be taking this medicine for a long time (more than 5 days in a row for children or 10 days in a row for adults), your doctor should check your progress at …Aug 16, 2023 · dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, chest pain, shortness of breath, uneven heartbeats, seizure). Common side effects of Alka-Seltzer Plus Night-Time Cold & Flu may include: feeling restless or excited. This is not a complete list of side effects and others may occur. Mar 22, 2024 · Alka-Seltzer Hangover Relief is usually taken every 6 hours with a full glass of water. Taking more than your recommended dose will not make Alka-Seltzer Hangover Relief more effective, and may cause serious side effects. Take with food if Alka-Seltzer Hangover Relief upsets your stomach. Lastly, in your question, you wanted to know about taking Alka-Seltzer after nitroglycerin, and that appears to be safe. Documented interactions have occurred when aspirin is given before nitroglycerin. So, overall, this interaction is thought to be a relatively minor one and probably not very likely to be of significance for most people.Apr 13, 2023 · Yes, it is safe to take Alka-Seltzer after drinking alcohol. However, it is important to note that it is not intended to be used as a treatment for alcohol intoxication or as a way to reduce the effects of a hangover. Alka-Seltzer works by providing relief from the symptoms of indigestion and upset stomach, which can be caused by drinking alcohol. Aug 16, 2023 · Common side effects of Alka-Seltzer Plus Day and Night Cold and Flu may include: drowsiness; constipation, diarrhea, upset stomach, vomiting; or. feeling restless or excited. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. We would like to show you a description here but the site won’t allow us. Can i take 1 advil (ibuprofen 200mg) and 2 alka seltzer plus (acetaminophen 325mg each) together? 3 doctors weighed in across 2 answers.

Yes, you can take Alka-Seltzer after taking ibuprofen, but it is important to be cautious. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can irritate the stomach lining and increase the risk of gastrointestinal ulcers. ... While there is no specific time frame for how long after taking Tylenol you can take Alka-Seltzer, it's ...

When can i take alka seltzer after taking naproxen. A member asked: Can i take alma seltzer with gabapentin and naproxen? A doctor has provided 1 answer. A member asked: 5 hrs ago my 16 yr old took alka-seltzer non-drowsy day time multi-sympton med. is he able to take either tylenol (acetaminophen) with codeine or naproxen 500mg now?Aug 16, 2023 · dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, chest pain, shortness of breath, uneven heartbeats, seizure). Common side effects of Alka-Seltzer Plus Night-Time Cold & Flu may include: feeling restless or excited. This is not a complete list of side effects and others may occur. Should i wait more than one day to breastfeed after taking alka-seltzer plus multi-symptom cold this also contains aspirin for fever, any suggestions ? A doctor has provided 1 answer. can i take alka seltzer while breastfeeding?: Depends: This is a group of products rather than one.Most are consider.Can you take alka seltzer plus cold and advil (ibuprofen)? A doctor has provided 1 answer. Dr. Heidi Fowler answered. Specializes in Psychiatry. According to the: Drugs.Com medication interaction checker- there is no significant interaction. Take care.May 13, 2023 · increased blood pressure. loss of appetite (continuing) mood or mental changes. muscle pain or twitching. ringing or buzzing in ears (continuing) skin rash, hives, or itching. slow breathing. swelling of face, fingers, ankles, feet, or lower legs. unpleasant taste. Can i take alka-seltzer while breastfeedin? Ask the baby: In all seriousness should not be an issue for you or baby. Maybe,maybe not: There are at least a dozen products carrying this name and some contain antihistamines or phenylephrine that can decrease milk volume, or Aspirin that should not be consumed iy baby may get a …Alka-Seltzer Anti-Gas side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Less serious side effects may be more likely, and you may have none at all. This is not a complete list of side effects and others may occur.Answer. It is safe to combine DayQuil and ibuprofen. There is no known drug interaction between them. It is important to note that there are several 'DayQuil' products available on the market, including: While all these products contain slightly different ingredients, they are all safe to take with ibuprofen.

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Apr 1, 2024 · Taking aspirin during this time may cause bleeding problems. For diabetic patients taking aspirin- or sodium salicylate-containing medicine: False urine sugar test results may occur: If you take 8 or more 325-mg doses of aspirin every day for several days in a row. If you take 8 or more 325-mg or 4 or more 500-mg doses of sodium salicylate. Took alka seltzer and advil liquid gels like 20 minutes later for my stomachache, that was 3 hrs agohow long do i have to wait before i can take my xanax (alprazolam)? 5 doctors weighed in across 2 answers Should be OK: This combo should not cause a problem. Some alka seltzer does contain acetaminophen (Tylenol), but also should be fine together. Read each individual package and be sure not to exceed the dosing recommended for either product. Answered 3/3/2021. 2.3k views. Specializes in Pediatrics. Ask own doctor: Tylenol has acetaminophen. Alka Seltzer Plus Cold has aspirin along with other ingredients. If taken together, they shouldn't cause an overdosing problem (because they don't have the same ingredients). However, if both are taken, a person would be doubling up on anti-inflammatory anti-pyretic pain ...If a mother chooses to use Alka-Seltzer Original while breastfeeding, she should take it immediately after breastfeeding. She should also be mindful of any potential side effects in her baby and contact a healthcare professional if she suspects that something may be wrong. In regards to Alka Seltzer Plus Cold, while it is generally safe to use ...Diflunisal: learn about side effects, dosage, special precautions, and more on MedlinePlus People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such a...Customer: Can I take alka seltzer plus cold together with Exederin Migraine? Doctor's Assistant: The Doctor can help. Just a couple quick questions before I transfer you. How long have you been concerned about the migraine? Customer: Get a massive one every couple of months Doctor's Assistant: Have you used Excedrin or anything similar …Should i wait more than one day to breastfeed after taking alka-seltzer plus multi-symptom cold this also contains aspirin for fever, any suggestions ? A doctor has provided 1 answer. can i take alka seltzer while breastfeeding?: Depends: This is a group of products rather than one.Most are consider.A doctor has provided 1 answer. Dr. Stephen Daquino answered. Specializes in Sports Medicine. Should be OK: This combo should not cause a problem. Some alka seltzer … ….

The recommended adult dose of Alka Seltzer Original is 2 tablets every 4 hours as needed, or as directed by a doctor - Do not exceed 8 tablets in 24 hours. There are various types of Alka Seltzer on the market. Check the box for full instructions if you are unsure or call your pharmacist.To use, fully dissolve tablets in 4 ounces of water before taking. Adults and children over 12 years old can take 2 tablets every 4 hours as needed, or as ...Obstetrics & Gynecology 44 years experience. Alka seltzer: If your alka selter contains aspirin, you should not take it. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5.1k views Reviewed >2 years ago. Thank. Dr. Alan Ali agrees. 1 thank. A 37-year-old member asked:Alka-Seltzer Anti-Gas side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Less serious side effects may be more likely, and you may have none at all. This is not a complete list of side effects and others may occur.If you must use both medications, take the ibuprofen at least 8 hours before or 30 minutes after you take the aspirin and caffeine (non-enteric coated form).Applies to: Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while … Alka-Seltzer Original Interactions. There are 440 drugs known to interact with Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate), along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 60 are major, 308 are moderate, and 72 are minor. Any pain relieving or anti-inflammatory medicines (e.g. ibuprofen) ... Avoid taking alcohol while taking Alka-Seltzer. ... Do not take Alka-Seltzer for more than 3 ...Using multivitamin with minerals together with levothyroxine may decrease the effects of levothyroxine. You should separate the administration of levothyroxine and multivitamin with minerals by at least 4 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications.Decongestants can pose a risk to people living with a thyroid disorder, such as an overactive thyroid ( hyperthyroidism) or an underactive thyroid ( hypothyroidism ). This is because ingredients like pseudoephedrine can affect the blood vessels throughout the body. Some drugs may interact with your thyroid medication. How long after taking ibuprofen can i take alka-seltzer, Apr 9, 2024 · mood changes; severe headache; or. severe dizziness or anxiety, feeling like you might pass out. Common side effects of Alka-Seltzer Plus Maximum Strength may include: dizziness, drowsiness; sleep problems ( insomnia ); diarrhea; or. feeling nervous, restless, anxious, or irritable. This is not a complete list of side effects and others may occur. , Spread the love. Proper use of Alka-Seltzer Anti-Gas Take this medicine after meals and at bedtime for best results. For patients taking the chewable tablet form of this medicine: It is important that you chew the tablets thoroughly before you swallow them. This is to allow the medicine to work faster and more completely., Can i take alka-seltzer while breastfeedin? Ask the baby: In all seriousness should not be an issue for you or baby. Maybe,maybe not: There are at least a dozen products carrying this name and some contain antihistamines or phenylephrine that can decrease milk volume, or Aspirin that should not be consumed iy baby may get a …, Mar 22, 2024 · Alka-Seltzer Hangover Relief is usually taken every 6 hours with a full glass of water. Taking more than your recommended dose will not make Alka-Seltzer Hangover Relief more effective, and may cause serious side effects. Take with food if Alka-Seltzer Hangover Relief upsets your stomach. , In general, you can take Alka-Seltzer Plus Severe Cold and Flu up to every 4 hours when you have common cold or flu symptoms. Make sure to read the directions on the package label to check how many times you can take Alka-Seltzer Plus Severe Cold and Flu in a 24-hour period. This can depend on the specific product you have., After taking Alka-Seltzer, how long should I take ibuprofen? Take ibuprofen at least 8 hours before or 30 minutes after taking aspirin and caffeine (non-enteric coated form) if you must use both medications. Is it possible to take ibuprofen in conjunction with Alka-Seltzer heartburn? Ibuprofen and Alka-Seltzer Heartburn Relief had no interactions., Medically reviewed by Drugs.com on Jul 26, 2023. Written by Cerner Multum. Uses. Side effects. Warnings. Before taking. Dosage. Interactions. The Alka-Seltzer Plus Cold …, Alka-Seltzer Plus Night-Time Cold & Flu. Generic name: acetaminophen, dextromethorphan, doxylamine, and phenylephrine [ ah-EET-a-MIN-oh-fen, DEX-troe-me-THOR-fan, dox-IL-a-meen, and-FEN-il-EFF-rin ] Brand names: Alka-Seltzer Plus Cold And Flu Day Night Maximum Strength, Alka-Seltzer Plus Day and Night Cold and Flu, Alka …, Alka-Seltzer Plus Night-Time Cold & Flu. Generic name: acetaminophen, dextromethorphan, doxylamine, and phenylephrine [ ah-EET-a-MIN-oh-fen, DEX-troe-me-THOR-fan, dox-IL-a-meen, and-FEN-il-EFF-rin ] Brand names: Alka-Seltzer Plus Cold And Flu Day Night Maximum Strength, Alka-Seltzer Plus Day and Night Cold and Flu, Alka …, There are 11 disease interactions with Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) which include: alcoholism. liver disease. cardiovascular disease. PKU. anticholinergic effects. asthma/COPD. cardiovascular. renal/liver disease., Should i wait more than one day to breastfeed after taking alka-seltzer plus multi-symptom cold this also contains aspirin for fever, any suggestions ? A doctor has provided 1 answer. can i take alka seltzer while breastfeeding?: Depends: This is a group of products rather than one.Most are consider., Alka-Seltzer contains aspirin, sodium bicarbonate, and citric acid, among other ingredients. Aspirin, in particular, can be a cause for concern during pregnancy. The use of aspirin has been associated with a condition called Reye's syndrome, which can cause serious liver and brain damage in infants and young children., 1. Talk to your doctor before using Alka-Seltzer to make sure it is safe. While Alka-Seltzer is typically safe to use, check in with your doctor before you decide to take it. Answer their questions about your medical history and let them know any concerns you have., Dizziness. Feeling nervous and excitable. Not able to sleep. Feeling sleepy. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088., 1. Talk to your doctor before using Alka-Seltzer to make sure it is safe. While Alka-Seltzer is typically safe to use, check in with your doctor before you decide to take it. Answer their questions about your medical history and let them know any concerns you have., Diflunisal: learn about side effects, dosage, special precautions, and more on MedlinePlus People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such a..., Tylenol can be taken on its own, but there are many multi-symptom cold & flu remedies that also contain acetaminophen as an active ingredient. These include: …, If you must use both medications, take the ibuprofen at least 8 hours before or 30 minutes after you take the aspirin and caffeine (non-enteric coated form). Avoid drinking alcohol while you are ... , Butazolidin is an NSAID (nonsteroidal anti-inflammatory drug). Butazolidin overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can ..., When considering taking Pepto Bismol and Alka Seltzer together, it is important to be aware of potential interactions between the two medications. While there is no known direct interaction, both medications can have similar side effects such as stomach upset and nausea. Combining them may increase the risk of experiencing these side effects., It typically takes about 2-3 minutes for Alka-Seltzer to take effect. After ingesting Alka-Seltzer, the active ingredient is absorbed into the bloodstream very quickly and its effects can usually be felt within a few minutes. It works by reducing the production of stomach acid and neutralizing the acid that’s already present., The recommended adult dose of Alka Seltzer Original is 2 tablets every 4 hours as needed, or as directed by a doctor - Do not exceed 8 tablets in 24 hours. There are various types of Alka Seltzer on the market. Check the box for full instructions if you are unsure or call your pharmacist., Can you take alka seltzer plus cold and advil (ibuprofen)? A doctor has provided 1 answer. Dr. Heidi Fowler answered. Specializes in Psychiatry. According to the: Drugs.Com medication interaction checker- there is no significant interaction. Take care., Alka-Seltzer Plus Cold 1 Acetaminophen is a pain reliever and fever reducer. 2 Important Information. Do not use Alka-Seltzer Plus Cold if you have used an MAO inhibitor in… 3 Before taking this medicine. You should not use this medication if you are allergic… 4 Use exactly as directed on…., Mylanta disease interactions. There are 4 disease interactions with Mylanta (aluminum hydroxide / magnesium hydroxide / simethicone) which include: constipation. inflammatory bowel disease. intestinal obstruction disorders. renal dysfunction., A cold may start with “just a tickle” in your throat, but before you know it, you’re in a full-out battle on more than one symptom front. Who has time for that? Take back your day with Alka-Seltzer Plus® Maximum Strength Sinus Congestion & Pain PowerMax® Gels that deliver concentrated power in a 25% smaller pill* to relieve your worst sinus and cold …, It is a myth that Alka Seltzer and other gas-generating substances cause seagulls to explode. Since seagulls can regurgitate the contents of their stomachs, they can eliminate unhe..., Unusual weight gain. Swelling or pain in the eyes, face, lips, or tongue. Decreased urination or cloudy urine. In terms of long-term side effects, excessive use of sodium bicarbonate, the primary ingredient in Alka-Seltzer, can lead to systemic alkalosis, where the body's pH balance becomes too alkaline., aspirin bismuth subsalicylate. Applies to: Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate) and Pepto-Bismol (bismuth subsalicylate) Using aspirin together with bismuth subsalicylate is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation ..., In conclusion, it is generally safe to take ibuprofen after taking Alka-Seltzer as long as you follow the dosage instructions and take necessary safety precautions. However, if you have any concerns or questions, you should consult with a …, When can i take alka seltzer after taking naproxen. A member asked: Can i take alma seltzer with gabapentin and naproxen? A doctor has provided 1 answer. A member asked: 5 hrs ago my 16 yr old took alka-seltzer non-drowsy day time multi-sympton med. is he able to take either tylenol (acetaminophen) with codeine or naproxen 500mg now?, Antacids (Alka-Seltzer, Gaviscon, Mylanta, Pepto-Bismol, Tums) – Reduces acidity in the stomach to immediately relieve mild heartburn. Histamine-2 receptor antagonists (famotidine [Pepcid, Zantac 360]) – Decreases stomach acid to relieve heartburn at night; most effective if taken daily., Alka-Seltzer Original Interactions. There are 440 drugs known to interact with Alka-Seltzer Original (aspirin/citric acid/sodium bicarbonate), along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 60 are major, 308 are moderate, and 72 are minor.